I tried it once. I had one hit, and did it with a friend. It takes 30-40 minutes to kick in, when it did it was amazing.
Make sure to go into it with a great mindset.
I got crazy awesome visuals and my friend and I both had a great time; it really does open up your creativity.
I did feel like shit the day after though, so I personally would only do it every once in a while, making sure I have nothing going on the day after.